PGx CYP450 drug response

Synonyms: Cytochrome P450 pharmacogenetics; CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5

Material:

EDTA blood
(1 ml), buccal swab

TAT:

10-15 days

Method:

NGS, amplicon-based

Overview

Individual differences in cytochrome P450 enzyme activity are a common cause of variable drug response, from treatment failure to severe adverse effects. This panel analyses seven major CYP450 pharmacogenes CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4 and CYP3A5 and reports genotype together with the corresponding metaboliser phenotype, where applicable. The included genes can be analysed either as part of the panel or individually for specific indications.

PGx CYP450 drug response

10 Gene(s)

CYP1A2, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP3A4, CYP3A5, CYP4F2

Pharmacological background

Tested variants

Result interpretation

Test limitations

Clinical relevance

References

Created by

Our editorial team consists of medical specialists and scientists in the field of human genetics. All content is created and reviewed in accordance with current scientific standards.

Last content review: August 4, 2026. As pharmacogenomic evidence and recommendations continue to evolve, the information presented on this page may not always reflect the latest updates. For current guidance and annotations, please refer to .

Last Update : 24.09.2026

How to order a genetic test

Select the right test for your patients. Contact our team in case you do not have an active contract yet.

Collect the sample. Download and fill in the order and consent form or access our portal (available for sample sent to Germany).

Properly pack the sample and send it to Medicover Genetics.

The sample will be analysed in our accredited laboratories.

An actionable report will be available for you to access safely and securely.

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