PreSENTIA: Breast High-Risk

Synonyms: -

Material:

Buccal swab

TAT:

2-3 weeks

Method:

NGS

Overview

Hereditary breast and specific types of gynecological cancers are considered some of the most common inherited types of cancer. Breast cancer is the most commonly diagnosed malignancy in women worldwide and arises from the accumulation of genetic and epigenetic alterations that drive uncontrolled proliferation of mammary epithelial cells. While most cases are sporadic, approximately 5–10% are hereditary and are associated with germline mutations in cancer susceptibility genes, particularly those involved in DNA repair pathways. Mutations on the genes tested in this panel have been identified to increase the risk of developing cancer in the future.

PreSENTIA Breast High-Risk cancer panel tests for numerous germline mutations in 7 genes that could cause breast, ovarian, endometrial or associated cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

PreSENTIA: Breast High-Risk

7 Gene(s)*

BRCA1

BRCA2

CDH1

PALB2

PTEN

STK11

TP53

Who is the test for

How many hereditary cancer syndromes are associated with this panel

References

Created by

Our editorial team consists of medical specialists and scientists in the field of human genetics. All content is created and reviewed in accordance with current scientific standards.

Last Update : 01.10.2026

How to order a genetic test

Select the right test for your patients. Contact our team in case you do not have an active contract yet.

Collect the sample. Download and fill in the order and consent form or access our portal (available for sample sent to Germany).

Properly pack the sample and send it to Medicover Genetics.

The sample will be analysed in our accredited laboratories.

An actionable report will be available for you to access safely and securely.

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